产品货号:
Z31656
中文名称:
DAZL抗体
英文名称:
Anti-DAZL Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DAZL Antibody |
指标别名 | DAZ homolog;DAZ like autosomal;DAZH;DAZL;DAZL1;DAZLA;deleted in azoospermia like;Deleted in azoospermia like 1;SPGY like autosomal;SPGYLA |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | DAZL |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human DAZL RNA-binding protein,which is essential for gametogenesis.Plays a central role during spermatogenesis.May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts. |
实际分子量 | 33KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Deleted in azoospermia-like is a protein that in humans is encoded by the DAZL gene.It is mapped to 3p24.3.The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females.The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes.In the testis,this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa.Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome.Mutations in this gene have been linked to severe spermatogenic failure and infertility in males.Two transcript variants encoding different isoforms have been found for this gene. |
Uniprot ID | Q92904 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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